This vacuum mesotherapy gun is a professional 3-in-1 water mesotherapy injector that combines single-needle injection, multi-needle injection and vacuum (negative-pressure) suction in one console.
It delivers hyaluronic acid, collagen, PRP and other skin-boosting solutions into the dermis at a precisely controlled depth, dose and speed, making it a reliable meso injector for aesthetic clinics, dermatology practices and medical spas.
Key Benefits of the Water Mesotherapy Gun
- Precise depth control : Single-needle depth 0.25–10 mm and multi-needle depth 0.25–5 mm for consistent, repeatable placement.
- Vacuum-assisted injection : Suction gently lifts and tensions the skin before the needles enter, helping place product evenly with less discomfort.
- Faster treatments : Multi-pin heads (3, 4, 5 and 9 needles) cover larger areas in fewer passes.
- Less product waste : Adjustable dose plus anti-backflow technology reduces solution and blood backflow.
- Easy operation : 4.3-inch LCD touch screen on the console and a digital display on the handpiece.
- Portable : Supplied in a lockable aluminium carry case for safe storage and transport between treatment rooms.
How the Vacuum Meso Injector Works
The injector uses vacuum technology to lift the skin slightly with negative pressure before the micro-needles enter. With the skin held taut, the multi-needle head deposits nutrients such as hyaluronic acid, collagen, PRP or PPC at an accurate, even depth typically around 1.28 mm into the dermis for skin-hydration protocols. Because hyaluronic acid can hold 200–300 times its weight in water, placing it directly in the dermis hydrates the skin from within, where topical creams that only reach the outer stratum corneum cannot.
Features of the Mesotherapy Machine
3-in-1 Injection Modes
- Single-needle mode for targeted, deeper injections (up to 10 mm).
- Multi-needle mode for fast, uniform superficial delivery (up to 5 mm).
- Vacuum mode with up to 90 kPa suction and 25 L/min flow.
Fully Adjustable Parameters
- Injection depth, dose, speed and suction intensity are all adjustable.
- Low-speed and high-speed modes from 10 to 250 shots per minute.
- Suitable for both endogenous (PRP) and exogenous (HA, collagen, vitamins) solutions.
Anti-Backflow Design
- Helps prevent solution and blood from flowing back into the line for cleaner, more hygienic sessions.
Mesotherapy Gun Specifications
| Specification | Detail |
|---|---|
| Product Type | Vacuum water mesotherapy gun / meso injector |
| Condition | New |
| Input Voltage | 110V / 240V, 50/60 Hz |
| Adapter Output | 12V / 5A |
| Power | 50 W |
| Display | 4.3-inch LCD touch screen |
| Functions | Single needle, multi-needle, vacuum (3-in-1) |
| Multi-Needle Heads | 3, 4, 5 and 9 needles |
| Speed Modes | Low speed / high speed, 10–250 times/min |
| Single Needle Caliber & Depth | 0.25 mm; 0.25–10 mm |
| Multi-Needle Caliber & Depth | 0.25 mm; 0.25–5 mm |
| Vacuum Flow / Pressure | 25 L/min / 90 kPa |
| Housing Material | Plastic |
| Colour | White with aqua-blue accents |
| Style | Portable, with aluminium carry case |
| Certification | CE |
| Package Size | 44 × 42 × 55 cm |
| Gross Weight | 8 kg |
What’s in the Box
- 1 × main machine with injector handpiece
- 3 × injection hypodermic needles
- 4 × syringes
- 1 × power connection cable
- 1 × aluminium carry case
- 1 × instruction manual
Applications & Treatment Areas
- Forehead, temple, periorbital, perioral and cheek photo-ageing
- Cheek and lip volume enhancement
- Atrophic and acne scar improvement
- Pore refinement and neck wrinkle improvement
- Fine lines, large pores and skin laxity
- Pigmentation concerns such as freckles, age spots and melasma
- Redness, telangiectasia, rosacea and erythema-prone skin
- Dull, oily or acne-prone skin, skin brightening and hydration
- Scalp and hair mesotherapy and PRP protocols
Who Is This Meso Injector For?
This water mesotherapy gun is designed for trained practitioners cosmetic physicians, dermatologists, aesthetic nurses and medical spa professionals who want faster, more consistent skin-booster and PRP injections than manual syringe techniques allow.
Frequently Asked Questions
What is a vacuum mesotherapy gun?
A vacuum mesotherapy gun is an automated injector that uses negative pressure to lift the skin, then injects solutions such as hyaluronic acid or PRP at a controlled depth and dose through single or multiple micro-needles.
What needle configurations does this mesotherapy gun support?
It supports single-needle injection and multi-needle heads with 3, 4, 5 or 9 needles, each with a 0.25 mm caliber.
How deep can this meso injector inject?
Single-needle depth is adjustable from 0.25 to 10 mm, and multi-needle depth from 0.25 to 5 mm.
Which solutions can be used with this water meso injector?
It is suitable for hyaluronic acid, collagen, PRP, PPC and other mesotherapy cocktails chosen by the practitioner.
What voltage does this mesotherapy gun run on?
It runs on 110V or 240V at 50/60 Hz, with a 12V/5A adapter output and 50 W power consumption.
Does the meso gun prevent backflow?
Yes. Anti-backflow technology helps stop solution and blood from flowing back into the line during treatment.
Related Mesotherapy Products
Complete your setup with our disposable mesotherapy gun catheters and 29G–34G ultra-fine hypodermic needles.
Comparing devices?
See the U225 PRP mesotherapy gun and the EZ negative pressure mesotherapy gun.



















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